Cat. No.: 317 005
Amount: 50 µg
Price:
$465.00
|
|
|
| Cat. No. 317 005 |
50 µg specific antibody, lyophilized. Affinity purified with the immunogen. Albumin and azide were added for stabilization. For reconstitution add 50 µl H2O to get a 1mg/ml solution in PBS. Then aliquot and store at -20°C to -80°C until use. Antibodies should be stored at +4°C when still lyophilized. Do not freeze! |
| Applications | |
| Immunogen | Recombinant protein corresponding to AA 775 to 905 from mouse ADAM22 (UniProt Id: Q9R1V6) |
| Reactivity |
Reacts with: rat, mouse (Q9R1V6). Other species not tested yet. |
| Specificity | Specific for ADAM 22. |
| Data sheet | 317_005.pdf |
|
|
ADAMs (a disintegrin and metalloproteinases) are a family of multidomain transmembrane glycoproteins.
With few exceptions most ADAM proteins are active zinc metalloproteinases. Members that lack functional metalloproteinase domains are implicated in protein-protein interactions instead of membrane protein ectodomain shedding. ADAM 22, one of these non-proteinase ADAMs acts as a receptor on the surface of the postsynaptic neuron and is involved in the regulation of synaptic signal transmission.
For more information on protein expression pattern, please refer to the overview image in our SYSY Antibodies ATLAS.